New paper in Aging Cell by Niels van den Berg
Today Aging Cell published the work of Niels van den Berg et al. showing that longevity is transmitted if persons belong to the oldest 10% survivors of their birth cohort and if at least 20% of their ancestors also belonged to the oldest 10% survivors.
In this study Niels van den Berg et al. showed that human longevity is transmitted for at least 2 subsequent generations only when at least 20% of a person’s relatives are long-lived. The analyses are based on a unique dataset, covering 37,825 persons from 1,326 five-generational families, in which living study participants are connected to their deceased ancestors. Our findings highlight the importance of using survival information of relatives/ancestors to avoid long-lived phenocopies in genetic studies and aim to stimulate cohort studies to extend their data with such ancestral information.