Connecting research to society


Prenatal famine drives DNA methylation and adult health six decades later

niod 85040DNA methylation, known to enable the activity of genes and be involved in development and metabolism, plays a key role in the link between prenatal famine exposure and body mass index and adult metabolic health, according to researchers at Leiden University Medical Center and Columbia University's Mailman School of Public Health. While earlier studies using animal models have illustrated the potential of epigenetics to influence health over the short run, this study in humans shows that the impact of a nutrition shock, like famine, on epigenetic markers in early life can still be linked to adult health, six decades later. The findings are published online in the journal Science Advances.

February 01 2018 Author: MolEpi

Connecting by collaboration to make a joint

Yolande Ramos of the Molepi osteoarthritis group is collaborating with Hossein Eslami Amirabadi of the Microsystems group at TU/e using a micofluidic device to create a model for a joint.

September 12 2017 Author: Molepi

BBMRI and Surfsara collaborate on genomic data

Genome researchers in the Netherlands are working in close cooperation in the field of omics data (such as genomic and metabolomic data) in the BBMRI-Omics consortium. Surfsara is intensively involved in the construction of the digital research environment, where omics-data can be shared and analysed.

July 13 2017 Author: MolEpi

Yotam Raz wins the James Joseph Award for best PhD-student presentation

On the 12th of June, Yotam Raz (PhD-student, Molecular Epidemiology) won the James Joseph Award at the annual conference of the American Aging Association for best PhD-student presentation. 2017 james joseph award for yotam raz

June 16 2017 Author: MolEpi

Ingrid appointed as professor molecular biology of osteoarthritis

The MolEpi group is very proud and happy to announce that as of March 2017, Dr Ingrid Meulenbelt is appointed as professor molecular biology of osteoarthiritis. With this appointment Ingrid is also attached to the department of Reumatology.

We wish her a lot of succes in future with her research and with fullfilling her new role!

May 12 2017 Author: Molepi

Lecture and meet-and-greet Diana Kuh on May 9 @ 3PM in lecture hall 2

Molecular Epidemiology is happy to announce the lecture by Professor Diana Kuh, PhD FFPH F MedSci at 3 PM on May 9 in lecture hall 2. The title of the lecture is:

From paediatrics to geriatrics: insights on ageing from a 70 year old British birth cohort study

May 08 2017 Author: Molepi - Molecular Epidemiology

New publication of Maarten van Iterson and collegues in Genome Biology

2017 pub maartenMaarten van Iterson, Erik van Zwet and Bas Heijmans published a new statistical method in Genome Biology that will improve the reproducibility of large-scale omics analyses.

January 30 2017 Author: Eka Suchiman

THE DYNAMIC EPIGENOME ACROSS THE LIFESPAN: From germ cells to disease, from development to ageing

A mini-symposium on the occasion of the thesis defence of Roderick Slieker that features state-of-the-art insights into the many faces of epigenetic regulation that drive development, ageing and disease, and into the potential of reversing disease-causing epigenetic changes.

December 22 2016 Author: MolEpi - Molecular Epidemiology

The association between metabolites and BMI is independent of fasting status

Although metabolites change after consumption of a meal, the association between metabolites and BMI is similar after a night of fasting and after a meal. Bianca Schutte investigated the Growing Old Together study and published her work in the scientific journal Scientific Reports.

December 15 2016 Author: Molepi - Molecular Epidemiology

Two new publications in Nature Genetics!

(press release)

Collaborating on big data to unravel disease processes

Patients with the same illness often receive the same treatment, even if the cause of the illness is different for each person. Six Dutch universities are combining forces to chart the different disease processes for a range of common conditions. This represents a new step towards ultimately being able to offer every patient more personalised treatment. The results of this study have been published in two articles in the authoritative scientific journal Nature Genetics.

December 05 2016 Author: Molepi - Moleculaire Epidemiology


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