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New publication of Maarten van Iterson and collegues in Genome Biology

2017 pub maartenMaarten van Iterson, Erik van Zwet and Bas Heijmans published a new statistical method in Genome Biology that will improve the reproducibility of large-scale omics analyses.

January 30 2017 Author: Eka Suchiman

THE DYNAMIC EPIGENOME ACROSS THE LIFESPAN: From germ cells to disease, from development to ageing

A mini-symposium on the occasion of the thesis defence of Roderick Slieker that features state-of-the-art insights into the many faces of epigenetic regulation that drive development, ageing and disease, and into the potential of reversing disease-causing epigenetic changes.

December 22 2016 Author: MolEpi - Molecular Epidemiology

The association between metabolites and BMI is independent of fasting status

Although metabolites change after consumption of a meal, the association between metabolites and BMI is similar after a night of fasting and after a meal. Bianca Schutte investigated the Growing Old Together study and published her work in the scientific journal Scientific Reports.

December 15 2016 Author: Molepi - Molecular Epidemiology

Two new publications in Nature Genetics!

(press release)

Collaborating on big data to unravel disease processes

Patients with the same illness often receive the same treatment, even if the cause of the illness is different for each person. Six Dutch universities are combining forces to chart the different disease processes for a range of common conditions. This represents a new step towards ultimately being able to offer every patient more personalised treatment. The results of this study have been published in two articles in the authoritative scientific journal Nature Genetics.

December 05 2016 Author: Molepi - Moleculaire Epidemiology

Research grant for Yolande Ramos in collaboration with Hossein Eslami Amirabadi

Following the first workshop in the project 2016 oa hdmt workshop'hDMT/NanoInside: Organs-on-Chips Technology Platform', the Institute for human Organ and Disease Model technologies (hDMT) has granted funding to pump and prime the project of Dr. Yolande Ramos (Molecular Epidemiology, LUMC) and Hossein Eslami Amirabadi (Microsystems group, TU Eindhoven).

October 19 2016 Author: Molepi - Molecular Epidemiology

the 6th Meeting of the EASD Study Group on Genetics of Diabetes (EASD-SGGD) is open for registration

the sixth Meeting of the EASD Study Group on Genetics of Diabetes (EASD-SGGD) will be organized next 11-13 May 2017 in Leiden and is open for registration!

 

October 04 2016 Author: Leen 't Hart - Molecular Epidemiology

Youthful DNA in old age

The DNA of young people is regulated to express the right genes at the right time. With the passing of years, the regulation of the DNA gradually gets disrupted, which is an important cause of ageing. A study of over 3,000 people shows that this is not true for everyone: there are people whose DNA appears youthful despite their advanced years. These are the findings of 34 researchers from six collaborating institutes led by Dr Bas Heijmans from the Leiden University Medical Center (the Netherlands), reported in Genome Biology.

September 22 2016 Author: Molecular Epidemiology - Molepi

Veni award for Elmar Tobi

Elmar Tobi has received a Veni award!

With this Veni award he will examine whether gestational diabetes increases a child’s risk on obesity and diabetes.

The working title of his grant proposal is "When does gestational diabetes leave a mark?"

July 15 2016 Author: Eka Suchiman

The environment to which we are exposed leaves its signature in our DNA

The environment to which people are exposed during their lifetime leaves its mark in their DNA. This is the result of research by scientists of the Netherlands Twin Register (NTR) from the Vrije Universiteit Amsterdam (VU) in collaboration with researchers at Leiden University Medical Center (LUMC) and the Avera Institute for Human Genetics located in Sioux Falls, SD (USA). The researchers discovered associations between the environment and DNA modifications by analyzing information surrounding the DNA sequence -  the so-called epigenome - from monozygotic (identical) and dizygotic (fraternal) twins. The results have been published today in Nature Communications.

April 12 2016 Author: MolEpi - Molecular Epidemiology

Save the date for the 6th EASD-SGGD meeting in 2017!

Coming meeting of the EASD study Group on Genetics of Diabetes (EASD-SGGD)  will be organised in Leiden, the Netherlands, May 11th - 13th, 2017

The local organisers are Leen 't Hart and Nienke van Leeuwen

March 29 2016 Author: Molepi - Molecular Epidemiology

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